1: 0.1 N (CH3)3CONa / diethyl ether; 2-methyl-propan-2-ol / 20 h / Ambient temperature 2: 61 percent / 10percent H2SO4 / methanol / 24 h / Ambient temperature 3: 1) mesitol, molecular sieve, 2) K, aniline / 1) pyridine, anh. methylcyclohexane, 10 h, irradiation, 2) liq. NH3 4: 64 percent / diisobutylaluminiumhydride / toluene View Scheme

2: Irradiation View Scheme

1: 0.1 N (CH3)3CONa / diethyl ether; 2-methyl-propan-2-ol / 20 h / Ambient temperature 2: 61 percent / 10percent H2SO4 / methanol / 24 h / Ambient temperature 3: 1) mesitol, molecular sieve, 2) K, aniline / 1) pyridine, anh. methylcyclohexane, 10 h, irradiation, 2) liq. NH3 View Scheme

1: hexamethylphosphoric acid triamide 2: HCl 3: p-TsOH, CH(OCH3)3 4: 1.) LiAlH4, 2.) TsCl, Py, 3.) LiBr 5: at -75 deg C to room temperature 6: 94 percent / deketalization 7: 0 °C 8: 86 percent / CsF / acetonitrile / 1.5 h / Heating View Scheme

1: 0.1 N (CH3)3CONa / diethyl ether; 2-methyl-propan-2-ol / 20 h / Ambient temperature 2: 61 percent / 10percent H2SO4 / methanol / 24 h / Ambient temperature 4: 49.4 mg / Cr(VI)-oxid, 95percent acetic acid / acetic acid / 2 h / Ambient temperature View Scheme