5-溴-7-氯-1H-吲唑合成路线 (共 2 条)
反应条件
1: With potassium tert-butylate in dimethyl sulfoxide T=20°C; 0.166667 h; Nitrogen atmosphere; 2: With hydrogenchloride in water; dimethyl sulfoxide T=4°C;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2003/104236 A1, 2003 ;
Location in patent: Page 122 ;
WO 03/104236 A1
反应条件
1: sodium nitrite; hydrogenchloride 2: potassium tert-butylate / dimethyl sulfoxide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 6 p. 1870 - 1873