2-甲基咪唑[4,5-C]吡啶合成路线 （共 8 条）
参考文献
Cooper, Kelvin; Fray, M. Jonathan; Parry, M. John; Richardson, Kenneth; Steele, John
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3115 - 3129
反应条件
acetic acid Cyclization; 1.5 h; Heating;
参考文献
Bakke; Riha
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 5 p. 1143 - 1145
反应条件
1: 97 percent / Et3N / acetonitrile / 1 h / 20 °C 2: 72 percent / N2O5 / nitromethane / 0.17 h / 0 °C 3: 97 percent / H2 / 5 percent Pd/C / methanol / 23 h / 20 °C / 5250.42 Torr 4: 97 percent / AcOH / 1.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 36, # 5 p. 1143 - 1145
反应条件
1: 72 percent / N2O5 / nitromethane / 0.17 h / 0 °C 2: 97 percent / H2 / 5 percent Pd/C / methanol / 23 h / 20 °C / 5250.42 Torr 3: 97 percent / AcOH / 1.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 36, # 5 p. 1143 - 1145
反应条件
1: 97 percent / H2 / 5 percent Pd/C / methanol / 23 h / 20 °C / 5250.42 Torr 2: 97 percent / AcOH / 1.5 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 36, # 5 p. 1143 - 1145
反应条件
ethanol; copper diacetate T=150°C;
参考文献
Chemische Berichte, , vol. 71, p. 2347,2358
反应条件
1: 46 percent / 30percent aq. H2O2, glacial AcOH / 144 h / 60 °C
2: 1.) K2CO3, 2.) Fe, glacial AcOH / 1.)DMF, 140 deg C, 16 h, 2.) 100 deg C, 30 min
View Scheme
参考文献
Cooper, Kelvin; Fray, M. Jonathan; Parry, M. John; Richardson, Kenneth; Steele, John
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3115 - 3129
