N-(4-甲氧基苯基)噻唑-2-胺合成路线 （共 4 条）
反应条件
toluene-4-sulfonic acid in isopropyl alcohol
T=80°C; 504 h;
参考文献
Schnuerch, Michael; Waldner, Birgit; Hilber, Karlheinz; Mihovilovic, Marko D.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 2149 - 2154
反应条件
t-Bu Brett Phos; water; palladium diacetate; potassium carbonate in tert-butyl alcohol
T=110°C; 3 h; Inert atmosphere;
参考文献
McGowan, Meredeth A.; Henderson, Jaclyn L.; Buchwald, Stephen L.
Organic Letters, 2012 , vol. 14, # 6 p. 1432 - 1435
反应条件
in ethanol; water
1 h; Heating / reflux;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2005/47273 A1, 2005 ;
Location in patent: Page/Page column 32 ;
WO 2005/047273 A1
参考文献
Forlani,L. et al.
Synthesis, 1977 , p. 320 - 322
