2-氰基-N-(2-甲氧基苯基)-乙酰胺合成路线 (共 2 条)
反应条件
1: anhydrous cyanoacetic acid With phosphorus pentachloride in dichloromethane
0.5 h; Reflux;
2: 2-methoxy-phenylamine in dichloromethane
2 h; Reflux;
参考文献
Hazeldine, Stuart; Pachaiyappan, Boobalan; Steinbergs, Nora; Nowotarski, Shannon; Hanson, Allison S.; Casero, Robert A.; Woster, Patrick M.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7378 - 7391
参考文献
Schellhase; Bohm; Pech
Pharmazie, 1984 , vol. 39, # 1 p. 19 - 21