1: aniline With hydrogenchloride; sodium nitrite in water
T=0 - 5°C; 1 h;
2: diethyl cyanosuccinate With pyridine in water
T=0 - 20°C; 2 h;
3: With hydrogenchloride; sodium hydroxide
more than 3 stages;
参考文献
IHARA CHEMICAL INDUSTRY CO., LTD.
Patent: EP1990336 A1, 2008 ;
Location in patent: Page/Page column 12 ;