bis(norbornadiene)rhodium(I) tetrafluoroborate; (11bM)-4-((1R,2S)-1-(diphenylphosphino)-3-methoxy-1-phenylprop-2-yloxy)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; hydrogen in tetrahydrofuran T=20°C; P=15001.5 Torr; 12 h; Autoclave; optical yield given as percent eeenantioselective reaction;

bis(norbornadiene)rhodium(I) tetrafluoroborate; (11bM)-4-((1R,2S)-1-(diphenylphosphino)-3-methoxy-1-phenylprop-2-yloxy)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; hydrogen in tetrahydrofuran T=20°C; P=15001.5 Torr; 12 h; Autoclave; optical yield given as percent ee;

bis(norbornadiene)rhodium(I) tetrafluoroborate; (11bM)-4-((1R,2S)-1-(diphenylphosphino)-3-methoxy-1-phenylprop-2-yloxy)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; hydrogen in tetrahydrofuran T=20°C; P=15001.5 Torr; 12 h; Autoclave; optical yield given as percent ee;

sodium hydroxide

<b>Multi-step reaction with 2 steps<br /> </b>1: 68 percent / HCl, hydroquinone / NH₄ReO₄ / ethyl acetate / 4 h<br />2: 92 percent / 14 h / 80 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>2: H₂O₂, HCOOH<br />3: 1) 2N aq. LiOH / 1) dioxane, RT, overnight, 2a) Et₂O, 0 deg C, 15 min, 2b) RT, 30 min<br />4: NEt₃ / CH₂Cl₂ / 0.75 h / 0 &deg;C<br />5: 6 percent / DBU, thiolacetic acid / dimethylformamide / 30 h / Ambient temperature<br /> <br /> &nbsp;