反应条件
1: 1.) POCl3; 2.) Zn / 1.) Et2O, reflux; 2.) AcOH, reflux
2: oxidation by culture of the bacteria Acinetobacter calcoaceticus NCIMB 9871
3: 95 percent / Me3SiI / CH2Cl2 / 0 deg C to r.t.
4: 95 percent / NaN3 / dimethylformamide / 75 °C
5: 95 percent / 1.) NaOH (2M); 2.) conc.HCl / Ambient temperature
6: 80 percent / 1.) H2; 2.) HCl gas / 1.) Pd-C / diethyl ether; ethanol / 760 Torr / Ambient temperature
View Scheme
参考文献
Mazzini, Claudio; Lebreton, Jacques; Alphand, Veronique; Furstoss, Roland
Tetrahedron Letters, 1997 , vol. 38, # 7 p. 1195 - 1196
