1,2-二氢-4-羟基-5-氯-1-甲基-2-氧代-喹啉-3-羧酸甲酯合成路线 （共 14 条）
反应条件
1.1: 1,4-dioxane / 12 - 20 °C
2.1: sodium hydride / mineral oil; N,N-dimethyl acetamide / 45 °C / |Inert atmosphere
2.2: 2 h / 20 °C / |Inert atmosphere
3.1: mineral oil; N,N-dimethyl acetamide / 5 h / 85 °C / |Inert atmosphere
View Scheme
参考文献
Wennerberg, Johan; Bjoerk, Anders; Fristedt, Tomas; Granquis, Bo; Jansson, Karl; Thuvesson, Ingela
Organic Process Research and Development, 2007 , vol. 11, # 4 p. 674 - 680
反应条件
T=100°C; 0.1 h; microwave irradiation;
参考文献
Jansson, Karl; Fristedt, Tomas; Olsson, Arne; Svensson, Bo; Joensson, Stig
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1658 - 1667
反应条件
T=100°C; 0.1 h; microwave irradiation;
参考文献
Jansson, Karl; Fristedt, Tomas; Olsson, Arne; Svensson, Bo; Joensson, Stig
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1658 - 1667
反应条件
water; trifluoroacetic acid in dimethyl sulfoxide; acetonitrile
T=50°C; 2 h; Kinetics;
参考文献
Jansson, Karl; Fristedt, Tomas; Olsson, Arne; Svensson, Bo; Joensson, Stig
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1658 - 1667
