cerium(III) chloride; sodium iodide in acetonitrile 3 h; Heating;

1.1: nBuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 70 percent / tetrahydrofuran; hexane / 3 h / -78 °C 2.1: cerium(III) chloride heptahydrate; sodium iodide / acetonitrile / 3 h / Heating 2.2: 80 percent / HCl / acetonitrile; H2O; diethyl ether View Scheme

lithium hydroxide; water in tetrahydrofuran; water T=20°C;