2-氯-3,4-二甲氧基-6-硝基苯甲酸合成路线 （共 2 条）
反应条件
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene in water; tert-butyl alcohol
T=20°C; 2 h;
参考文献
SANKYO COMPANY, LIMITED; X-CEPTOR THERAPEUTICS, INC.
Patent: WO2003/106435 A1, 2003 ;
Location in patent: Page 330 ;
WO 03/106435 A1
反应条件
1: nitric acid / 2 h / 0 - 65 °C
2: potassium permanganate; water / acetone / 1 h / 60 - 70 °C
View Scheme
参考文献
NOVARTIS AG; DECHANTSREITER, Michael A.; GROB, Jonathan E.; MAC SWEENEY, Aengus; MILTZ, Wolfgang; RANDL, Stefan; SEDRANI, Richard; SELLNER, Holger; SIROCKIN, Finton; VALEUR, Eric
Patent: WO2013/192345 A1, 2013 ;
