5-氯咪唑并[1,2-a]吡嗪合成路线 （共 2 条）
反应条件
in ethylene glycol dimethyl ether; water T=60°C; 1.5 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; AUSTIN, Joel, Francis; SHARMA, Lisa, S.; BALOG, James, Aaron; HUANG, Audris; VELAPARTHI, Upender; DARNE, Chetan, Padmakar; SAULNIER, Mark, George
Patent: WO2012/15723 A1, 2012 ;
Location in patent: Page/Page column 106; 107 ;
WO 2012/015723 A1
反应条件
hydrogen bromide; sodium hydrogencarbonate in isopropyl alcohol Reflux;
参考文献
NOVARTIS AG; BOCK, Mark G.; GAUL, Christoph; GUMMADI, Venkateshwar Rao; SENGUPTA, Saumitra
Patent: WO2010/149755 A1, 2010 ;
Location in patent: Page/Page column 196-197 ;
WO 2010/149755 A1
