反应条件
1: 1.) a) n-BuLi, CuI, 2.) O2 / 1.) a) THF, hexane, -78 deg C, 1 h, b) THF, -25 deg C, 1 h, 2.) CH2Cl2, RT, 8h 2: 92 percent / 1.) a) phosphoryl chloride / dimethylformamide / 1.) a) 0 deg C, 2 h, b) 80 deg C, 1 h 3: 89 percent / KOH, H2 / 10percent Pd/C / methanol / 3 h / 760 Torr / Ambient temperature View Scheme
参考文献
Shiao, Min-Jen; Tarng, Kai-Yih
Heterocycles, 1990 , vol. 31, # 4 p. 637 - 641
