2-乙基-3-甲基-丁酸乙酯合成路线 （共 11 条）
反应条件
ammonia; sodium amide
参考文献
Hudson; Hauser
Journal of the American Chemical Society, 1940 , vol. 62, p. 2459
Journal of the American Chemical Society, 1941 , vol. 63, p. 3161
反应条件
Pd-BaSO4 in diethyl ether
168 h; Ambient temperature;
参考文献
Kirmse, Wolfgang; Rode, Jutta; Rode, Klaus
Chemische Berichte, 1986 , vol. 119, # 12 p. 3672 - 3693
反应条件
sodium ethanolate
T=150 - 160°C;
参考文献
Roland; McElvain
Journal of the American Chemical Society, 1937 , vol. 59, p. 134
反应条件
water; lithium diisopropyl amide in tetrahydrofuran
1) -78 deg C, 30 min 2) 30 min;
参考文献
Lion, Claude; Lebbar, Kadija; Boukou-Poba, Jean-Paul
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 3 p. 227 - 234
反应条件
triphenylmethyl-sodium
und Aethylierung der entstandenen Natriumverbindung mit Benzolsulfonsaeure-aethylester oder auch mit Aethyljodid;
参考文献
Hudson; Hauser
Journal of the American Chemical Society, 1940 , vol. 62, p. 2459
Journal of the American Chemical Society, 1941 , vol. 63, p. 3161
反应条件
1: 1.) NaNH2 / 1.) ether, 24 h, reflux, 2.) ether, 30 min, reflux
2: 29 percent Chromat. / H2 / Pd(5percent)/C / diethyl ether / Ambient temperature
View Scheme
参考文献
Kirmse, Wolfgang; Rode, Jutta; Rode, Klaus
Chemische Berichte, 1986 , vol. 119, # 12 p. 3672 - 3693
反应条件
1: ethanol; NaI / bei 70-stdg. Kochen
2: sodium ethylate / 150 - 160 °C
View Scheme
参考文献
Roland; McElvain
Journal of the American Chemical Society, 1937 , vol. 59, p. 134
反应条件
hydrogen; 5-palladium/activated carbon in diethyl ether
Ambient temperature;
参考文献
Kirmse, Wolfgang; Rode, Jutta; Rode, Klaus
Chemische Berichte, 1986 , vol. 119, # 12 p. 3672 - 3693
反应条件
die entstehende Natriumverbindung reagiert mit Aethyljodid in Aether;
参考文献
Hudson; Hauser
Journal of the American Chemical Society, 1940 , vol. 62, p. 2459
Journal of the American Chemical Society, 1941 , vol. 63, p. 3161
反应条件
(i) iPr2NH, nBuLi, pentane, THF, (ii) /BRN= 505934/, HMPT; Multistep reaction;
参考文献
MacPhee,J.A.; Dubois,J.-E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 694 - 696
