3-甲基-2-丁烯酸乙酯合成路线 （共 160 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=130°C; 8 h;
参考文献
Kawase, Yoshiyuki; Yamaguchi, Seiji; Horita, Hisanori; Takeno, Junko; Kameyama, Hideaki
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 4 p. 1153 - 1155
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=130°C; 8 h;
参考文献
Kawase, Yoshiyuki; Yamaguchi, Seiji; Horita, Hisanori; Takeno, Junko; Kameyama, Hideaki
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 4 p. 1153 - 1155
反应条件
AlCl3, aluminium chloride
5 h; Reflux;
参考文献
Zheng, Baisong; Yao, Yuan; Liu, Zhen; Deng, Lisheng; Anglin, Justin L.; Jiang, Hong; Prasad, B.V. Venkataram; Song, Yongcheng
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 542 - 546
反应条件
1: 1.) Dibal, 2.) MnO2 / 1.) ether, -78 deg C, 30 min, 2.) ethylacetate, 6 h
2: NaH / tetrahydrofuran
View Scheme
参考文献
Sheves, Mordechai; Nakanishi, Koji
Journal of the American Chemical Society, 1983 , vol. 105, # 12 p. 4033 - 4039
反应条件
ammonia in ethanol
T=80°C; 22 h;
参考文献
Thaisrivongs; Pals; DuCharme; Turner; DeGraaf; Lawson; Couch; Williams
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 633 - 642
参考文献
Philippi; Galter
Monatshefte fuer Chemie, 1929 , vol. 51, p. 264
反应条件
sodium hydride
T=-10 - 20°C; Michael-Claisen cyclization; 0.666667 h; Inert atmosphereneat (no solvent); regioselective reaction;
参考文献
Sharma, Dharminder; Shil, Arun K.; Singh, Bikram; Das, Pralay
Synlett, 2012 , vol. 23, # 8 p. 1199 - 1204
参考文献
Wahl
Annales de Chimie (Cachan, France), 1912 , vol. <8>25, p. 426
反应条件
1: Oxone(R); aq. HBr / CH2Cl2 / 2 h / 20 °C
2: Et3N / CH2Cl2 / 12 h / 20 °C
View Scheme
参考文献
Murfitt; Roberts
Journal of the Chemical Society, 1944 , p. 372
反应条件
bromine; Petroleum ether
参考文献
Babler; Invergo
Tetrahedron Letters, 1981 , vol. 22, # 29 p. 2743 - 2746
