双[2-(2-氯化乙氧基)乙基]醚合成路线 （共 59 条）
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate T=65°C; 72 h;
参考文献
Gibson, Harry W.; Bheda, Mukesh C.; Engen, Paul; Shen, Ya Xi; Sze, Jean; et al.
Journal of Organic Chemistry, 1994 , vol. 59, # 8 p. 2186 - 2196
反应条件
potassium hydroxide T=80°C; 48 h;
参考文献
Ashikaga, Kazuo; Ito, Shinzaburo; Yamamoto, Masahide; Nishijima, Yasunori
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 7 p. 2443 - 2450
反应条件
sodium iodide in acetone
96 h; Heating;
参考文献
Jousselme, Bruno; Blanchard, Philippe; Levillain, Eric; Delaunay, Jacques; Allain, Magali; Richomme, Pascal; Rondeau, David; Gallego-Planas, Nuria; Roncali, Jean
Journal of the American Chemical Society, 2003 , vol. 125, # 5 p. 1363 - 1370
反应条件
1: 52 percent / aq. NaOH / butan-1-ol / Heating
2: 68 percent / HIO4; I2; H2SO4 / acetic acid; H2O / 16 h / 70 °C
View Scheme
参考文献
Kimura, Masaru; Shi, Kun; Hashimoto, Koji; Hu, Zhi Zhi
Heterocycles, 2006 , vol. 68, # 11 p. 2375 - 2380
反应条件
1: NaI / acetone / 70 h / Heating
2: 54 percent / Na2CO3 / acetonitrile / 18 h / Heating
3: 85 percent / H2 / Pd/C / acetic acid / 15 h / 60 °C / 2280 Torr
4: 1.) K2CO3, 2.) LiAlH4 / 1.) THF, 2.) RT, 18 h
View Scheme
参考文献
Calverley, Martin J.; Dale, Johannes
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 4 p. 241 - 248
反应条件
1: 65 percent
2: 70 percent / PPA / 6 h / 70 °C
View Scheme
参考文献
Beger, J.; Meerbote, M.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 5 p. 923 - 926
反应条件
sodium hydroxide in 1,4-dioxane
24 h; Heating;
参考文献
Ctech, Bronislav
Tetrahedron Letters, 1980 , vol. 21, p. 4197 - 4198
反应条件
lithium bromide; lithium tert-butylate
1.) tert-Butanol, reflux, 2.) reflux, ca. 12 d; Yield given. Multistep reaction;
参考文献
Gloe, K.; Muehl, P.; Beger, J.; Poeschmann, C.; Petrich, M.; Beyer, L.
Journal fuer Praktische Chemie (Leipzig), 1991 , vol. 333, # 3 p. 413 - 421
反应条件
sodium carbonate in toluene
20 h; Heating;
参考文献
Krakowiak, Krzysztof E.; Bradshaw, Jerald S.; Izatt, Reed M.
Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3364 - 3368
反应条件
sodium hydroxide in butan-1-ol
35 h; Heating;
参考文献
Beger, J.; Meerbote, M.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 5 p. 923 - 926
