二(2-甲基-2-丙基)4-氨基-2,6-吡啶二羧酸酯合成路线 （共 4 条）
反应条件
palladium on activated charcoal; hydrogen in methanol; ethyl acetate
T=20°C; P=2585.74 Torr; 12 h;
参考文献
Huang, Baohua; Prantil, Matthew A.; Gustafson, Terry L.; Parquette, Jon R.
Journal of the American Chemical Society, 2003 , vol. 125, # 47 p. 14518 - 14530
反应条件
1: 1.79 g / 4-dimethylaminopyridine; pyridine / CH2Cl2 / 16 h / 20 °C
2: 97 percent / NaN3 / dimethylformamide / 24 h / 50 °C
3: 98 percent / Pd/C; H2 / ethyl acetate; methanol / 12 h / 20 °C / 2585.74 Torr
View Scheme
参考文献
Huang, Baohua; Prantil, Matthew A.; Gustafson, Terry L.; Parquette, Jon R.
Journal of the American Chemical Society, 2003 , vol. 125, # 47 p. 14518 - 14530
反应条件
1: POCl3 / 12 h / 128 °C
2: 1.79 g / 4-dimethylaminopyridine; pyridine / CH2Cl2 / 16 h / 20 °C
3: 97 percent / NaN3 / dimethylformamide / 24 h / 50 °C
4: 98 percent / Pd/C; H2 / ethyl acetate; methanol / 12 h / 20 °C / 2585.74 Torr
View Scheme
参考文献
Huang, Baohua; Prantil, Matthew A.; Gustafson, Terry L.; Parquette, Jon R.
Journal of the American Chemical Society, 2003 , vol. 125, # 47 p. 14518 - 14530
反应条件
1: 97 percent / NaN3 / dimethylformamide / 24 h / 50 °C
2: 98 percent / Pd/C; H2 / ethyl acetate; methanol / 12 h / 20 °C / 2585.74 Torr
View Scheme
参考文献
Huang, Baohua; Prantil, Matthew A.; Gustafson, Terry L.; Parquette, Jon R.
Journal of the American Chemical Society, 2003 , vol. 125, # 47 p. 14518 - 14530
