6-甲氧基-n,2-二甲基苯并呋喃-3-羧酰胺合成路线 （共 4 条）
反应条件
boron tribromide in dichloromethane T=-5 - 0°C; 2 h;
参考文献
PFIZER INC.
Patent: WO2005/63739 A1, 2005 ;
Location in patent: Page/Page column 51 ;
WO 2005/063739 A1
反应条件
in tetrahydrofuran
T=20°C; 1 h;
参考文献
PFIZER INC.
Patent: WO2005/63739 A1, 2005 ;
Location in patent: Page/Page column 51 ;
WO 2005/063739 A1
反应条件
1: 6-methoxy-2-methyl-benzofuran-3-carboxylic acid With 1,1'-carbonyldiimidazole in 2-MeTHF
2: methylamine in 2-MeTHF; water
T=0 - 45°C;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/66181 A2, 2007 ;
Location in patent: Page/Page column 25-26 ;
WO 2007/066181 A2
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US2004/9965 A1, 2004 ;
