4-氨基-N-甲基-N-苯基苯磺酰胺合成路线 （共 9 条）
反应条件
1: 65 percent / H2O / 40 h / Heating
2: 80 percent / 50percent HCl, NaNO2 / H2O
3: acetic anhydride / 3 h / Heating
4: 58 percent / HCl / 2 h / Heating
View Scheme
参考文献
Tikare, Ravindra K.; Badami, Bharati V.; Puranik, Gurubasav S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 7 p. 673 - 677
反应条件
in water
40 h; Heating;
参考文献
Tikare, Ravindra K.; Badami, Bharati V.; Puranik, Gurubasav S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 7 p. 673 - 677
反应条件
1: 65 percent / H2O / 40 h / Heating
2: 80 percent / 50percent HCl, NaNO2 / H2O
View Scheme
参考文献
Tikare, Ravindra K.; Badami, Bharati V.; Puranik, Gurubasav S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 7 p. 673 - 677
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=750.06 Torr;
参考文献
Zheng, Xiaoxia; Oda, Hiroyuki; Takamatsu, Kayo; Sugimoto, Yukio; Tai, Akihiro; Akaho, Eiichi; Ali, Hamed Ismail; Oshiki, Toshiyuki; Kakuta, Hiroki; Sasaki, Kenji
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 2 p. 1014 - 1021
参考文献
Zeneca Limited
Patent: US5510386 A1, 1996 ;
反应条件
1: 76 percent / sodium hydride / dimethylformamide / 1 h / 20 °C
2: 80 percent / H2 / Pd/C / ethanol / 750.06 Torr
View Scheme
参考文献
Zheng, Xiaoxia; Oda, Hiroyuki; Takamatsu, Kayo; Sugimoto, Yukio; Tai, Akihiro; Akaho, Eiichi; Ali, Hamed Ismail; Oshiki, Toshiyuki; Kakuta, Hiroki; Sasaki, Kenji
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 2 p. 1014 - 1021
反应条件
1: pyridine
2: aqueous hydrochloric acid
View Scheme
参考文献
Lur'e; Rostkowskaja
Zhurnal Obshchei Khimii, 1944 , vol. 14, p. 137,140
Chem.Abstr., 1945 , p. 2288
反应条件
1: pyridine
2: aqueous hydrochloric acid
View Scheme
参考文献
Lur'e; Rostkowskaja
Zhurnal Obshchei Khimii, 1944 , vol. 14, p. 137,140
Chem.Abstr., 1945 , p. 2288
反应条件
hydrogenchloride
1) Et2O, reflux; 2) reflux; Yield given. Multistep reaction;
参考文献
Empfield; Mayhugh; Ohnmacht; Frank; Grant; Li
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 7 p. 775 - 778
