(4-甲基苯基)吗啉-4-基甲酮合成路线 （共 37 条）
反应条件
tris(2,4-di-tert-butyl-phenyl) phosphite; potassium methanolate; [Ni(O2CCH3)2]*4H2O in diethylene glycol dimethyl ether
T=110°C; 10 h;
参考文献
Jo, Youngshin; Ju, Jinhun; Choe, Jaehoon; Kwang, Ho Song; Lee, Sunwoo
Journal of Organic Chemistry, 2009 , vol. 74, # 16 p. 6358 - 6361
反应条件
Zr(NMe2)4 in toluene
T=25°C; 10 h; Inert atmosphere;
参考文献
Stephenson, Nickeisha A.; Zhu, Jiang; Gellman, Samuel H.; Stahl, Shannon S.
Journal of the American Chemical Society, 2009 , vol. 131, # 29 p. 10003 - 10008
反应条件
in tetrahydrofuran; hexane
T=0°C; 0.166667 h; Inert atmosphere;
参考文献
Park, Jae Kyo; Shin, Won Kyu; An, Duk Keun
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 5 p. 1592 - 1594
反应条件
Zr(NMe2)4 in toluene
T=90°C; 12 h; Inert atmosphere;
参考文献
Stephenson, Nickeisha A.; Zhu, Jiang; Gellman, Samuel H.; Stahl, Shannon S.
Journal of the American Chemical Society, 2009 , vol. 131, # 29 p. 10003 - 10008
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.5 h; Microwave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.5 h; Microwave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.5 h; Microwave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
1: 4-methyl-benzoic acid With thionyl chloride
Reflux;
2: morpholine in dichloromethane
T=0 - 20°C; 0.166667 h;
参考文献
Melomedov, Jascha; Ochsmann, Julian Robert; Meister, Michael; Laquai, Frederic; Heinze, Katja
European Journal of Inorganic Chemistry, 2014 , # 11 p. 1984 - 2001
反应条件
tert.-butylhydroperoxide; 2,2'-azo-bisisobutyronitrile in water; acetonitrile
T=80°C; 24 h; Mechanism;
参考文献
Vanjari, Rajeshwer; Guntreddi, Tirumaleswararao; Singh, Krishna Nand
Green Chemistry, 2014 , vol. 16, # 1 p. 351 - 356
反应条件
1: thionyl chloride; N,N-dimethyl-formamide / toluene / 15 h / 80 °C / Inert atmosphere
2: triethylamine / dichloromethane / 0 - 20 °C
View Scheme
参考文献
Gonzalez-Lopez, Susana; Yus, Miguel; Ramon, Diego J.
Tetrahedron Asymmetry, 2012 , vol. 23, # 8 p. 611 - 615
