2-溴-4-氯-1-硝基苯合成路线 （共 13 条）
反应条件
oxygen; silver carbonate; potassium hydroxide; copper(ll) bromide in dimethyl sulfoxide; N,N-dimethyl-formamide T=130 - 140°C;
参考文献
Luo, Yong; Pan, Xiaolin; Wu, Jie
Tetrahedron Letters, 2010 , vol. 51, # 50 p. 6646 - 6648
反应条件
sodium perborate; acetic acid T=60°C; 3 h;
参考文献
Tasler, Stefan; Kraus, Juergen; Wuzik, Andreas; Mueller, Oliver; Aschenbrenner, Andrea; Cubero, Elena; Pascual, Rosalia; Quintana-Ruiz, Jordi-Ramon; Dordal, Alberto; Merce, Ramon; Codony, Xavier
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 22 p. 6224 - 6229
反应条件
sulfuric acid; nitric acid
反应条件
KNO2; hydrogen bromide; dimethyl sulfoxide in water T=35°C; 0.166667 h;
参考文献
Baik, Woonphil; Luan, Wanqiang; Lee, Hyun Joo; Yoon, Cheol Hun; Koo, Sangho; Kim, Byeong Hyo
Canadian Journal of Chemistry, 2005 , vol. 83, # 3 p. 213 - 219
参考文献
Gazzetta Chimica Italiana, , vol. 4, p. 341
Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, , p. 317
反应条件
1.1: tetrahydrofuran / -40 °C 2.1: nBuLi / tetrahydrofuran / -70 °C 2.2: TsN3 / tetrahydrofuran / -70 - -40 °C 3.1: Red-Al / tetrahydrofuran / -40 - 0 °C View Scheme
参考文献
Owa, Takashi; Okauchi, Tatsuo; Yoshimatsu, Kentaro; Sugi, Naoko Hata; Ozawa, Yoichi; Nagasu, Takeshi; Koyanagi, Nozomu; Okabe, Tadashi; Kitoh, Kyosuke; Yoshino, Hiroshi
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 11 p. 1223 - 1226
参考文献
Jacobsen, E. Jon; Stelzer, Lindsay S.; Belonga, Kenneth L.; Carter, Donald B.; Im, Wha Bin; Sethy, Vimala H.; Tang, Andrew H.; Von Voigtlander, Philip F.; Petke, James D.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3820 - 3836
反应条件
copper(l) iodide; potassium carbonate; N-methyl-N-(phenylcarbonyl)amine in toluene T=110°C; 20 h;
参考文献
Tasler, Stefan; Mies, Jan; Lang, Martin
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 14-15 p. 2286 - 2300
反应条件
potassium phosphate; copper(l) iodide in toluene T=110°C; 20 h;
参考文献
Tasler, Stefan; Mies, Jan; Lang, Martin
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 14-15 p. 2286 - 2300
反应条件
potassium phosphate; copper(l) iodide in toluene T=110°C; 20 h; Further byproducts.;
参考文献
Tasler, Stefan; Mies, Jan; Lang, Martin
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 14-15 p. 2286 - 2300
