3-溴-5-((2-三甲基硅烷基)乙炔基)吡啶合成路线 （共 3 条）
反应条件
potassium hydroxide in methanol; water T=15 - 20°C; 2 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/94822 A1, 2005 ;
Location in patent: Page/Page column 36 ;
WO 2005/094822 A1
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride in acetonitrile
16 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/94822 A1, 2005 ;
Location in patent: Page/Page column 36 ;
WO 2005/094822 A1
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride
T=20°C;
参考文献
Tominaga, Masahide; Kato, Masanori; Okano, Takashi; Sakamoto, Shigeru; Yamaguchi, Kentaro; Fujita, Makoto
Chemistry Letters, 2003 , vol. 32, # 11 p. 1012 - 1013
