1-N-丙基-3,7-二甲基黄嘌呤合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol; N,N-dimethyl-formamide
P=2068.6 Torr; 0.333333 h;
参考文献
Daly, J. W.; Padgett, W. L.; Shamim, M. T.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 7 p. 1305 - 1308
反应条件
1: 3,7-dimethyl xanthine With sodium hydride in dimethyl sulfoxide
T=60°C; 0.333333 h; Inert atmosphere;
2: 1-propylhalide in dimethyl sulfoxide
T=60°C; Inert atmosphere;
参考文献
Larsen, Aaron T.; May, Erin M.; Auclair, Karine
Journal of the American Chemical Society, 2011 , vol. 133, # 20 p. 7853 - 7858
反应条件
sodium hydroxide in isopropyl alcohol
T=120°C; 24 h; Yield given;
参考文献
Madyastha; Sridhar
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 6 p. 677 - 680
参考文献
van der Slooten
Archiv der Pharmazie (Weinheim, Germany), 1897 , vol. 235, p. 471
Recueil des Travaux Chimiques des Pays-Bas, 1896 , vol. 15, p. 188
Chem. Zentralbl., 1897 , vol. 68, # I p. 284
反应条件
T=165 - 170°C; 1 h; Yield given;
参考文献
Kowalska, Alicja; Maslankiewicz, Andrzej; Syrek, Barbara; Cieplinski, Piotr
Monatshefte fuer Chemie, 1985 , vol. 116, p. 341 - 352
参考文献
Biltz; Max
Justus Liebigs Annalen der Chemie, 1921 , vol. 423, p. 320
Full Text Show Details
Biilmann; ter Braak
Recueil des Travaux Chimiques des Pays-Bas, 1929 , vol. 48, p. 919,920
