4-(甲基氨基)-3,5-二甲苯酚合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
4 h; Inert atmosphereCooling with iceReflux;
参考文献
Ieda, Naoya; Nakagawa, Hidehiko; Peng, Tao; Yang, Dan; Suzuki, Takayoshi; Miyata, Naoki
Journal of the American Chemical Society, 2012 , vol. 134, # 5 p. 2563 - 2568
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / acetonitrile / 1 h / 20 °C
2.1: acetic anhydride / 1 h / 0 °C
2.2: 0.67 h / 20 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Inert atmosphere; Cooling with ice; Reflux
View Scheme
参考文献
Ieda, Naoya; Nakagawa, Hidehiko; Peng, Tao; Yang, Dan; Suzuki, Takayoshi; Miyata, Naoki
Journal of the American Chemical Society, 2012 , vol. 134, # 5 p. 2563 - 2568
反应条件
1.1: acetic anhydride / 1 h / 0 °C
1.2: 0.67 h / 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Inert atmosphere; Cooling with ice; Reflux
View Scheme
参考文献
Ieda, Naoya; Nakagawa, Hidehiko; Peng, Tao; Yang, Dan; Suzuki, Takayoshi; Miyata, Naoki
Journal of the American Chemical Society, 2012 , vol. 134, # 5 p. 2563 - 2568
