1: 1.) nBuLi / 1.) THF, hexane, -40 deg C, 1 h, 2.) THF, hexane, RT, 24 h 2: 78 percent / NaBH4 / methanol / 18 h / Ambient temperature 3: 67 percent / thionyl chloride / CH2Cl2 / 5 h / Ambient temperature 4: 21 percent / dimethylformamide / 1 h / Ambient temperature View Scheme

1: 67 percent / thionyl chloride / CH2Cl2 / 5 h / Ambient temperature 2: 21 percent / dimethylformamide / 1 h / Ambient temperature View Scheme

1: 78 percent / NaBH4 / methanol / 18 h / Ambient temperature 2: 67 percent / thionyl chloride / CH2Cl2 / 5 h / Ambient temperature 3: 21 percent / dimethylformamide / 1 h / Ambient temperature View Scheme

in N,N-dimethyl-formamide 1 h; Ambient temperature;