1-(1-甲基乙基)-1H-1,2,4-噻唑合成路线 （共 3 条）
反应条件
1: 1H-1,2,4-triazol With sodium methylate in methanol
2: 2-iodo-propane in methanol
T=5 - 80°C; 0.75 h; Microwave irradiation;
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/147188 A1, 2009 ;
Location in patent: Page/Page column 99-100 ;
WO 2009/147188 A1
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=0 - 20°C; Alkylation;
参考文献
Bulger, Paul G.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf-H.
Tetrahedron Letters, 2000 , vol. 41, # 8 p. 1297 - 1301
参考文献
Dash, Chandrakanta; Shaikh, Mobin M.; Ghosh, Prasenjit
Journal of Chemical Sciences, 2011 , vol. 123, # 2 p. 97 - 106
