[2-(2-氯苯基)噻唑-4-基]甲醇合成路线 （共 6 条）
反应条件
diisobutylaluminium hydride in dichloromethane; toluene
T=-78°C; 1 h;
参考文献
PHARMACIA and UPJOHN COMPANY; FINZEL, Barry, C.
Patent: WO2004/2977 A1, 2004 ;
Location in patent: Page 23-24 ;
WO 2004/002977 A1
反应条件
methanesulfonic acid; carbonic acid dimethyl ester
T=120°C; 3 h; Microwave irradiation;
参考文献
Orr, David; Tolfrey, Alexandra; Percy, Jonathan M.; Frieman, Joanna; Harrison, Zoe A.; Campbell-Crawford, Matthew; Patel, Vipulkumar K.
Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9655 - 9662
反应条件
1: pyridine; hydrogen sulfide; triethylamine
2: toluene / 2 h / Reflux
3: sulfuric acid; water / Reflux
View Scheme
参考文献
Mahmoodi, Majid; Aliabadi, Alireza; Emami, Saeed; Safavi, Maliheh; Rajabalian, Saeed; Mohagheghi, Mohammad-Ali; Khoshzaban, Ahad; Samzadeh-Kermani, Alireza; Lamei, Navid; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2010 , vol. 343, # 7 p. 411 - 416
反应条件
1: toluene / 2 h / Reflux
2: sulfuric acid; water / Reflux
View Scheme
参考文献
Mahmoodi, Majid; Aliabadi, Alireza; Emami, Saeed; Safavi, Maliheh; Rajabalian, Saeed; Mohagheghi, Mohammad-Ali; Khoshzaban, Ahad; Samzadeh-Kermani, Alireza; Lamei, Navid; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2010 , vol. 343, # 7 p. 411 - 416
反应条件
1: P2S5/alumina / tetrahydrofuran / 0.33 h / 60 °C / |Microwave irradiation
2: methanesulfonic acid; carbonic acid dimethyl ester / 3 h / 120 °C / |Microwave irradiation
View Scheme
参考文献
Orr, David; Tolfrey, Alexandra; Percy, Jonathan M.; Frieman, Joanna; Harrison, Zoe A.; Campbell-Crawford, Matthew; Patel, Vipulkumar K.
Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9655 - 9662
参考文献
Bazargan, Leila; Shafiee, Abbas; Amini, Mohsen; Dezfouli, Ebrahim Bakhshi; Azizi, Ebrahim; Ghaffari, Seyed Mahmood
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 3 p. 602 - 609
