6-氨基-3-[(2-氟苯基)甲基]-2,4(1H,3H)-嘧啶二酮合成路线 (共 1 条)
反应条件
1: NaNO2; aq. AcOH / 85 - 100 °C
2: H2 / PtO2 / ethanol / 2740.88 Torr
3: EDCI; imidazole; DMAP / dimethylformamide
View Scheme
参考文献
Foley, Louise H.; Wang, Ping; Dunten, Pete; Ramsey, Gwendolyn; Gubler, Mary-Lou; Wertheimer, Stanley J.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 21 p. 3871 - 3874