6-甲氧基-3,4-二氢-1-萘甲腈合成路线 （共 12 条）
反应条件
hydrogenchloride; AlCl3; ZnI2 in sodium hydroxide; water; ethyl acetate; benzene
参考文献
Abbott Laboratories
Patent: US5128362 A1, 1992 ;
反应条件
toluene-4-sulfonic acid in tetrahydrofuran; hexane; water; N,N-dimethyl-formamide; toluene
参考文献
Abbott Laboratories
Patent: US5248677 A1, 1993 ;
反应条件
1: ZnI2 2: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 7 p. 1049 - 1062
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=60°C; 24 h; DDQ/substrate ratio = 2;
参考文献
Lemaire, Marc; Doussot, Joel; Guy, Alain
Chemistry Letters, 1988 , # 10 p. 1581 - 1584
反应条件
pyridine; trichlorophosphate RefluxInert atmosphere;
参考文献
Betik, Robert; Kotora, Martin
European Journal of Organic Chemistry, 2011 , # 18 p. 3279 - 3282
反应条件
hydrogenchloride in ethanol
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 7 p. 1049 - 1062
参考文献
Journal of the American Chemical Society, , vol. 94, p. 4654 - 4672
反应条件
1: 85 percent / 2,3-dihydro-5,6-dicyano-1,4-benzoquinone / benzene / 2 h / Heating 2: 80 percent / NaOH, H2O / methanol / 20 h / Heating View Scheme
参考文献
Amin, Shantu; Hecht, Stephen S.; Hoffmann, Dietrich
Journal of Organic Chemistry, 1981 , vol. 46, # 11 p. 2394 - 2398
反应条件
1: sulfur, 5percent Pd/C / 2 h / 190 - 200 °C 2: NaCN / dimethylsulfoxide / 12 h / 160 - 170 °C View Scheme
参考文献
Reddy, P. Aravinda; Reddy, A. Babul; Reddy, G. Ramachandra; Reddy, N. Subbarami
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 6 p. 1451 - 1456
反应条件
1: t-BuOOH, tetrabutylammonium fluoride 2: 8 percent / H3O(1+) View Scheme
参考文献
Pryde, David C.; Henry, Steven S.; Meyers
Tetrahedron Letters, 1996 , vol. 37, # 19 p. 3243 - 3246
