in methanol T=20 - 35°C; 6 h;

PbO in methanol Reflux;

1: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / 1,4-dioxane / 3.5 h / 100 °C / |Inert atmosphere; |Large scale 2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,4-dioxane; water / 7.5 h / 20 - 88 °C / |Inert atmosphere; |Large scale View Scheme

(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in 1,4-dioxane T=20 - 110°C; 2 h; Inert atmosphere;

1: Br2 / CHCl3 / 10 - 15 °C 2: aq. HCl / Heating View Scheme

bromine in chloroform T=10 - 15°C;