5-甲基-2-氨基苯并恶唑合成路线 (共 8 条)
反应条件
(i) MeOH, (ii) H2O; Multistep reaction;
参考文献
Journal of Pharmaceutical Sciences, , vol. 53, p. 538 - 544
反应条件
tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; acetic acid in water; acetonitrile T=80°C; 2 h; Inert atmosphere;
参考文献
Kloeckner, Ulrich; Weckenmann, Nicole M.; Nachtsheim, Boris J.
Synlett, 2012 , # 1 art. no. D23611ST, p. 97 - 100
反应条件
tert.-butylhydroperoxide; Manganese (II) acetate; 4-methoxy-benzoic acid in water; acetonitrile T=70°C; 12 h;
参考文献
Kim, Ji Young; Cho, Seung Hwan; Joseph, Jomy; Chang, Sukbok
Angewandte Chemie - International Edition, 2010 , vol. 49, # 51 p. 9899 - 9903
反应条件
1: aq. HCl 2: PbO / methanol / Heating View Scheme
参考文献
Journal of Pharmaceutical Sciences, , vol. 53, p. 538 - 544
反应条件
sodium hydroxide Heating;
参考文献
Chemische Berichte, , vol. 97, p. 1599 - 1608
反应条件
in acetone 4 h; Heating;
参考文献
Synthetic Communications, , vol. 20, # 5 p. 693 - 701
反应条件
in acetone 4 h; Heating;
参考文献
Synthetic Communications, , vol. 20, # 5 p. 693 - 701
反应条件
in acetone
4 h; Heating;
参考文献
Sambaiah, T.; Reddy, K. Kondal
Synthetic Communications, 1990 , vol. 20, # 5 p. 693 - 701