叔丁氧羰酰基6-氨基己酸合成路线 （共 35 条）
反应条件
sodium hydroxide in 1,4-dioxane T=20°C; 3 h;
参考文献
Biraboneye, Alain Cesar; Madonna, Sebastien; Laras, Younes; Krantic, Slavica; Maher, Pamela; Kraus, Jean-Louis
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4358 - 4369
反应条件
triethylamine in 1,4-dioxane; water T=20°C; 23 h; Inert atmosphere;
参考文献
3R VALO, S.E.C.; BERUBE, Gervais; DESCOTEAUX, Caroline; ASSELIN, Eric
Patent: WO2011/11865 A1, 2011 ;
Location in patent: Page/Page column 32-33 ;
反应条件
sodium hydroxide in 1,4-dioxane; water; ethyl acetate
参考文献
Cytogen Corporation
Patent: US5585468 A1, 1996 ;
反应条件
4-(polystyrylMeO)-2,2,6,6-tetraMepiperidin-1-yloxy radical; PS-CH2Me3(+)*ClO2(-); PS-CH2NMe3(+)*H2PO4(-); potassium bromide in water; acetonitrile T=20°C; 36 h;
参考文献
Yasuda, Kosuke; Ley, Steven V.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 8 p. 1024 - 1025
反应条件
1: CH2Cl2 / 3 h / 0 °C 2: PDC / dimethylformamide / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 8, # 6 p. 1253 - 1262
反应条件
sodium hydroxide in tert-butyl alcohol 12 h;
参考文献
Doughty; Chaurasia; Li
Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 272 - 279
反应条件
triethylamine in 1,4-dioxane; water
参考文献
Lippard, Stephen J.; Barnes, Carmen M.; Haskel, Ariel; Barnes, Katie R.
Patent: US2004/235712 A1, 2004 ;
Location in patent: Page/Page column 34 ;
反应条件
water; magnesium oxide in 1,4-dioxane T=50°C; 26 h;
参考文献
Mikhura, I. V.; Formanovskii, A. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 2 p. 205 - 212
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 2 p. 247 - 255
反应条件
phosphate-buffered silica gel supported KMnO4 in cyclohexane T=20°C;
参考文献
Takemoto; Yasuda; Ley
Synlett, 2001 , # 10 p. 1555 - 1556
反应条件
sodium hydroxide in 1,4-dioxane
