4-甲基亚硝胺基-1-3-吡啶基-1-丁酮合成路线 (共 3 条)
反应条件
sodium nitrite in water 16 h; Ambient temperaturepH 4;
参考文献
Pathak, Tanmaya; Thomas, Noel F.; Akhtar, Mahmoud; Gani, David
Tetrahedron, 1990 , vol. 46, # 5 p. 1733 - 1744
反应条件
cytochrome P450 reductase pH=7; aq. phosphate bufferEnzymatic reaction;
参考文献
Krishnan, Sadagopan; Wasalathanthri, Dhanuka; Zhao, Linlin; Schenkman, John B.; Rusling, James F.
Journal of the American Chemical Society, 2011 , vol. 133, # 5 p. 1459 - 1465
反应条件
carbonyl reductase EC 1.1.1.184; NADPH-regenerating system in water T=37°C; Reduction; pH=7.4; 0.5 h; Enzyme kinetics; Further Variations:pH dependence; co-substrate dependence; inhibition with medicines;
参考文献
Atalla; Breyer-Pfaff; Maser
Xenobiotica, 2000 , vol. 30, # 8 p. 755 - 769