1: sodium wire / diethyl ether / 18 h / Ambient temperature
2: ethanol / 7 h / Heating
3: 77 percent / NaOH / H2O; ethanol / 60 °C
4: 34 percent / 2.) ethanolic hydrogen chloride / 5 h / 145 - 150 °C
View Scheme
参考文献
Brown, Thomas H.; Blakemore, Robert C.; Blurton, Peter; Durant, Graham J.; Ganellin, C. Robin; et al.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 65 - 72
