5-甲基-2-硝基苯甲腈合成路线 （共 21 条）
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
hydrogenchloride; tin
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
1: 51 percent / SnCl2*2H2O, conc. HCl / 0.25 h / below 40 deg C 2: 58 percent / 1N-HCl / 1.5 h / Heating View Scheme
参考文献
Werbel; Elslager; Newton
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 345 - 349
反应条件
1: fuming hydrochloric acid / 150 °C / im geschlossenen Rohr 2: tin; hydrochloric acid 3: Diazotization.nachfolgend Erhitzen mit Wasser View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
1: With hydrogenchloride; tin(ll) chloride in ethanol; water T=20 - 30°C; 1 h; 2: With sodium hydroxide in ethanol; water pH=7;
参考文献
SENOMYX, INC.
Patent: US2008/306053 A1, 2008 ;
Location in patent: Page/Page column 60 ;
反应条件
1: tin; hydrochloric acid / <30 2: hydrochloric acid; water; NaNO2 / Diazotization.man laesst die Diazoloesung zu einer 40grad warmen Loesung aus CuSO4, KCN und Wasser fliessen View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
1: Fe, AcOH 2: (i) HNO2, aq. HBF4, (ii) (pyrolysis) View Scheme
参考文献
Journal of Organic Chemistry, , vol. 43, # 2 p. 220 - 224
反应条件
1: fuming hydrochloric acid / 150 °C / im geschlossenen Rohr 2: tin; hydrochloric acid 3: 120 - 130 °C View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
1: fuming hydrochloric acid / 150 °C / im geschlossenen Rohr 2: tin; hydrochloric acid View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
1: 51 percent / SnCl2*2H2O, conc. HCl / 0.25 h / below 40 deg C
2: 58 percent / 1N-HCl / 1.5 h / Heating
3: 72 percent / triethylamine / dioxane / 0.33 h / Heating
4: 70 percent / 1,3-dibromo-5,5-dimethylhydantoin, benzoyl peroxide / CCl4 / 0.33 h / Heating; Irradiation
5: K2CO3 / dimethylformamide / 4 h / 75 °C
6: NaOCH3 / methanol / 1.5 h / Heating
View Scheme
参考文献
Werbel; Elslager; Newton
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 345 - 349
