5-甲基-2-硝基苯甲腈合成路线 （共 21 条）
反应条件
1: 51 percent / SnCl2*2H2O, conc. HCl / 0.25 h / below 40 deg C
2: 58 percent / 1N-HCl / 1.5 h / Heating
3: 72 percent / triethylamine / dioxane / 0.33 h / Heating
4: 70 percent / 1,3-dibromo-5,5-dimethylhydantoin, benzoyl peroxide / CCl4 / 0.33 h / Heating; Irradiation
5: NaH / toluene / 2 h / 75 °C
6: 0.75 g / NaOCH3 / methanol / 0.75 h / Heating
View Scheme
参考文献
Werbel; Elslager; Newton
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 345 - 349
