(2-氧代-1-苯肼)乙酸合成路线 （共 11 条）
反应条件
in methanol 3 h; Irradiation;
参考文献
Chow, Yuan L.; Horning, Douglas P.; Polo, Joel
Canadian Journal of Chemistry, 1980 , vol. 58, p. 2477 - 2483
参考文献
Fischer,O.
Chemische Berichte, 1899 , vol. 32, p. 248
参考文献
Fischer,O.
Chemische Berichte, 1899 , vol. 32, p. 248
反应条件
1: acetic anhydride / 5 h / 100 °C 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
Fang, Yuesi; Wu, Chunrui; Larock, Richard C.; Shi, Feng
Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 8840 - 8851
反应条件
tetrachlorosilane; silica gel; sodium nitrite in dichloromethane
T=0 - 5°C; 2.5 h;
参考文献
Azarifar, Davood; Bosra, Hassan Ghasemnejad; Zolfigol, Mohammad-Ali; Tajbaksh, Mahmood
Heterocycles, 2006 , vol. 68, # 1 p. 175 - 181
反应条件
1.1: sodium hydroxide / water / 0.5 h / Reflux
1.2: pH 2
2.1: hydrogenchloride; sodium nitrite / water / 2.5 h / 0 °C
View Scheme
参考文献
Nithinchandra; Kalluraya; Aamir; Shabaraya
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 597 - 604
反应条件
1.1: sodium acetate / ethanol / 6 h / Reflux
2.1: sodium hydroxide / water / 0.5 h / Reflux
2.2: pH 2
3.1: hydrogenchloride; sodium nitrite / water / 2.5 h / 0 °C
View Scheme
参考文献
Nithinchandra; Kalluraya; Aamir; Shabaraya
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 597 - 604
反应条件
(i) EtOH, (ii) aq. HNO2; Multistep reaction;
参考文献
Ogata; Kawasaki; Kojoh
The Journal of organic chemistry, 1974 , vol. 39, # 25 p. 3676 - 3679
参考文献
Schwebel
Chemische Berichte, 1878 , vol. 11, p. 1128
反应条件
1: acetic anhydride / 5 h / 100 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 20 °C
View Scheme
参考文献
Fang, Yuesi; Wu, Chunrui; Larock, Richard C.; Shi, Feng
Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 8840 - 8851
