3-[(氨基亚胺甲基)氨基]-4-甲基苯甲酸乙酯硝酸盐合成路线 （共 5 条）
反应条件
1: With hydrogenchloride in ethanol T=90°C; 15.25 h; 2: With ammonium nitrate in water T=5 - 10°C; 1 h;
参考文献
WO2004/5281 A1, ;
Page 37 ;
WO 2004/005281 A1
反应条件
1: sulfuric acid / 12 h / |Reflux; |Inert atmosphere 2: hydrogenchloride / ethanol; water / 15 h / |Reflux 3: ammonium nitrate / 0.5 h / 0 °C View Scheme
参考文献
Chemical Biology and Drug Design, , vol. 83, # 5 p. 592 - 599
反应条件
1: hydrogenchloride / ethanol; water / 15 h / |Reflux 2: ammonium nitrate / 0.5 h / 0 °C View Scheme
参考文献
Chemical Biology and Drug Design, , vol. 83, # 5 p. 592 - 599
反应条件
ammonium nitrate T=0°C; 0.5 h;
参考文献
Pan, Xiaoyan; Dong, Jinyun; Gao, Hongping; Wang, Fang; Zhang, Yanmin; Wang, Sicen; Zhang, Jie
Chemical Biology and Drug Design, 2014 , vol. 83, # 5 p. 592 - 599
反应条件
1: sodium hydroxide / butan-1-ol / 72 h / |Reflux; |Inert atmosphere 2: sodium hydroxide / ethanol; water / 4 h / 45 - 50 °C View Scheme
参考文献
Pan, Xiaoyan; Dong, Jinyun; Gao, Hongping; Wang, Fang; Zhang, Yanmin; Wang, Sicen; Zhang, Jie
Chemical Biology and Drug Design, 2014 , vol. 83, # 5 p. 592 - 599
