2,5-二氯-3-苯基吡嗪合成路线 （共 30 条）
反应条件
trichlorophosphate
T=180 - 185°C; 5 h; high pressure;
参考文献
Sato, Nobuhiro
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 149 - 152
反应条件
trichlorophosphate
T=170°C;
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
trichlorophosphate
T=170°C;
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
trichlorophosphate
T=170°C;
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
1: 49 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1) r.t., overnight, 2) reflux, 3 h
2: POCl3 / 0.5 h / Heating
View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: aqueous NaOH
2: POCl3
3: methanol
4: aqueous H2O2; acetic acid
5: POCl3
6: aqueous HCl; acetic acid
7: POCl3 / 170 °C
View Scheme
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
1: POCl3
2: methanol
3: aqueous H2O2; acetic acid
4: POCl3
5: aqueous HCl; acetic acid
6: POCl3 / 170 °C
View Scheme
参考文献
Karmas; Spoerri
Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076
反应条件
1: 34 percent / KOH / ethanol / 5 h / Heating
2: 76 percent / 90percent H2O2, maleic anhydride / CH2Cl2 / 1) r.t., overnight, 2) reflux, 2 h
3: 1 h / Heating
4: 10percent KOH / methanol / 1 h / Heating
5: POCl3, PCl5 / 1 h / 160 °C
6: 74 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1) r.t., overnight, 2) reflux, 3 h
7: POCl3 / 0.5 h / Heating
View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: 76 percent / 90percent H2O2, maleic anhydride / CH2Cl2 / 1) r.t., overnight, 2) reflux, 2 h
2: 1 h / Heating
3: 10percent KOH / methanol / 1 h / Heating
4: POCl3, PCl5 / 1 h / 160 °C
5: 74 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1) r.t., overnight, 2) reflux, 3 h
6: POCl3 / 0.5 h / Heating
View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: 1 h / Heating
2: 10percent KOH / methanol / 1 h / Heating
3: POCl3, PCl5 / 1 h / 160 °C
4: 74 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1) r.t., overnight, 2) reflux, 3 h
5: POCl3 / 0.5 h / Heating
View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
