螺[1-氮杂双环[2.2.2]辛烷-3,2’-环氧乙烷] 盐酸盐合成路线 （共 3 条）
反应条件
1: trimethyl-oxo-sulfonium iodide With potassium tert-butylate in dimethyl sulfoxide T=25 - 30°C; 0.5 h; Inert atmosphere; 2: 1-azabicyclo[2.2.2]-octan-3-one hydrochloride in dimethyl sulfoxide T=25°C; 8 h; Inert atmosphere;
参考文献
Pramanik, Chinmoy; Patil, Pradip; Kotharkar, Sandeep; Tripathy, Narendra K.; Gurjar, Mukund K.
Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3043 - 3045
反应条件
hydrogen sulfide; sodium hydroxide in water T=45°C; 2.5 h;
参考文献
Pramanik, Chinmoy; Patil, Pradip; Kotharkar, Sandeep; Tripathy, Narendra K.; Gurjar, Mukund K.
Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3043 - 3045
反应条件
1: hydrogen sulfide; sodium hydroxide / water / 2.5 h / 45 °C 2: boron trifluoride diethyl etherate / dichloromethane View Scheme
参考文献
Pramanik, Chinmoy; Patil, Pradip; Kotharkar, Sandeep; Tripathy, Narendra K.; Gurjar, Mukund K.
Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3043 - 3045
