2,4-二氧代-5-甲基-己酸乙酯合成路线 （共 7 条）
反应条件
1: With sodium in ethanol T=0 - 80°C; 1.75 h; 2: With sulfuric acid in ethanol; water T=15 - 25°C; pH=2;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 45, 46 ;
US 20030236287 A1
反应条件
hydrogenchloride in 3-methyl-butan-2-one; ethanol; ethyl acetate
参考文献
US2003/195205 A1, ;
US 20030195205 A1
反应条件
hydroxylamine hydrochloride in ethanol T=15 - 25°C; 1 h; Heating / reflux;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 45, 46 ;
US 20030236287 A1
反应条件
1: With sodium hydrogencarbonate in methanol T=0 - 60°C; 2 h; 2: With sodium hydroxide in methanol; water T=80°C; 2 h; 3: With hydrogenchloride in methanol; water pH=3;
参考文献
Sun, Yufeng; Qiao, Huili; Ling, Yun; Yang, Shaoxiang; Rui, Changhui; Pelosi, Paolo; Yang, Xinling
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 6 p. 2456 - 2461
反应条件
hydrazine monohydrochloride in tetrahydrofuran; ethanol; water T=75°C; 1 h;
参考文献
Pfizer Inc.
Patent: US2004/220186 A1, 2004 ;
Location in patent: Page 18 ;
US 20040220186 A1
反应条件
1: 76 percent / NH2OH*HCl / ethanol / 2 h / Heating 2: 71 percent / LiAlH4 / tetrahydrofuran / 0.5 h / -78 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 47 p. 7509 - 7512
反应条件
1: K2CO3; acetone
2: aqueous H2SO4
View Scheme
参考文献
Libermann et al.
Bulletin de la Societe Chimique de France, 1958 , p. 687,691
