反应条件
1.1: tributyltinhydride; PdCl2(PPh3)2 / tetrahydrofuran / 1 h / -78 °C
1.2: 55 percent / N-iodosuccinimide / tetrahydrofuran / 0.17 h / 0 - 20 °C
2.1: 87 percent / 4-(dimethylamino)pyridine; triethylamine; PdCl2(MeCN)2 / dimethylformamide / 6 h / 20 °C / 22800 Torr
3.1: 82 percent / TBAF; AcOH / CH2Cl2 / 24 h / 20 °C
4.1: 78 percent / 4-(dimethylamino)pyridine; triethylamine; PdCl2(MeCN)2 / dimethylformamide / 12 h / 20 °C / 22800 Torr
5.1: aq. AcOH / tetrahydrofuran / 48 h / 20 °C
6.1: Zn dust; aq. NH4OAc / tetrahydrofuran / 2 h / 20 °C
7.1: 2,2'-dipyridyl disulfide; PPh3 / toluene / 1 h / 20 °C
7.2: 40 percent / AgOTf / toluene / 0.5 h / 20 °C
8.1: 87 percent / trifluoroacetic acid / CH2Cl2 / 6 h / 20 °C
View Scheme
参考文献
Kusaka, Shin-Ichi; Dohi, Suguru; Doi, Takayuki; Takahashi, Takashi
Tetrahedron Letters, 2003 , vol. 44, # 49 p. 8857 - 8859
