6-氨基-3-碘-5-硝基-2(1H)-吡啶酮合成路线 （共 4 条）
反应条件
N-iodo-succinimide in N,N-dimethyl-formamide
T=20°C; 96 h;
参考文献
Huttert, Daniel; Benner, Steven A.
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9839 - 9842
反应条件
in water; N,N-dimethyl-formamide
参考文献
Benner, Steven Albert
Patent: US8053212 B1, 2011 ;
反应条件
1.1: 71 percent / m-chloroperbenzoic acid / acetone / 72 h / 20 °C
2.1: KOAc; Ac2O / 0.25 h / Heating
2.2: 12 percent / NH3 / methanol / 20 h / 20 °C
3.1: 81 percent / N-iodosuccinimide / dimethylformamide / 96 h / 20 °C
View Scheme
参考文献
Huttert, Daniel; Benner, Steven A.
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9839 - 9842
反应条件
1: 75 percent / aq. NaOH / ethanol / 0.08 h / Heating
2: 81 percent / N-iodosuccinimide / dimethylformamide / 96 h / 20 °C
View Scheme
参考文献
Huttert, Daniel; Benner, Steven A.
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9839 - 9842
