1.1: 58 percent / K2CO3 / dimethylformamide / 20 °C 2.1: NaH / dimethylformamide / 0 °C 2.2: 84 percent / dimethylformamide / 2.75 h / 0 - 20 °C 3.1: 89 percent / HCl / ethyl acetate / 20 °C View Scheme
参考文献
Hart, Matthew E.; Suchland, Katherine L.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1101 - 1112