4-(羟基甲基)-1-苯基-2-吡咯烷酮合成路线 （共 4 条）
反应条件
methanol; sodium tetrahydroborate in tetrahydrofuran
2 h; Heating;
参考文献
Watanabe, S.; Ogawa, K.; Ohno, T.; Yano, S.; Yamada, H.; Shirasaka, T.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 9 p. 675 - 686
反应条件
1: 90.5 percent / conc. H2SO4 / CH2Cl2 / Heating
2: 95.5 percent / NaBH4, MeOH / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Watanabe, S.; Ogawa, K.; Ohno, T.; Yano, S.; Yamada, H.; Shirasaka, T.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 9 p. 675 - 686
反应条件
1: 93.3 percent / Heating
2: 90.5 percent / conc. H2SO4 / CH2Cl2 / Heating
3: 95.5 percent / NaBH4, MeOH / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Watanabe, S.; Ogawa, K.; Ohno, T.; Yano, S.; Yamada, H.; Shirasaka, T.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 9 p. 675 - 686
反应条件
1: 93.3 percent / Heating
2: 90.5 percent / conc. H2SO4 / CH2Cl2 / Heating
3: 95.5 percent / NaBH4, MeOH / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Watanabe, S.; Ogawa, K.; Ohno, T.; Yano, S.; Yamada, H.; Shirasaka, T.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 9 p. 675 - 686
