N6-苯甲酰基-5'-O-(4,4'-二甲氧基三苯基)-2'-脱氧腺苷合成路线 （共 17 条）
反应条件
silica gel; trifluoroacetic acid in methanol; chloroform
参考文献
Pathak, Ashish K.; Pathak, Vibha; Seitz, Lainne E.; Tiwari, Kamal N.; Akhtar, Mohammad S.; Reynolds, Robert C
Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7755 - 7757
反应条件
zinc dibromide in methanol; chloroform 12 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 22, # 38 p. 3761 - 3764
反应条件
saccharin-N-methylimidazole salt T=20°C; 5 - 7 h;
参考文献
AVECIA BIOTECHNOLOGY INC.; AVECIA LIMITED
Patent: WO2004/35599 A1, 2004 ;
Location in patent: Page 9-10 ;
反应条件
chloro-trimethyl-silane in tetrahydrofuran 1 h; Ambient temperature;
参考文献
Dabkowski, Wojciech; Tworowska, Izabela; Michalski, Jan; Cramer, Friedrich
Chemical Communications, 1997 , # 9 p. 877 - 878
反应条件
1: N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine With N-ethyl-N,N-diisopropylamine in dichloromethane 0.166667 h; 2: (N,N-diisopropylamino)-(2-cyanoethoxy)chlorophosphine With [C6mim][FAP] 1.75 h;
参考文献
Amigues, Eric J.; Hardacre, Christopher; Keane, Gillian; Migaud, Marie E.; Norman, Sarah E.; Pitner, William R.
Green Chemistry, 2009 , vol. 11, # 9 p. 1391 - 1396
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran; acetonitrile 0.166667 h; Ambient temperature;
参考文献
Zhang, Zhaoda; Tang, Jin Yan
Tetrahedron Letters, 1996 , vol. 37, # 3 p. 331 - 334
反应条件
methylamine in methanol
T=20°C; 16 h;
参考文献
Kurata, Christine; Bradley, Kym; Gaus, Hans; Luu, Nhuy; Cedillo, Isaiah; Ravikumar, Vasulinga T.; Sooy, Kent Van; McArdle, James V.; Capaldi, Daniel C.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 3 p. 607 - 614
