甲酯2-(4-羟基-3-甲基苯基)乙酸合成路线 （共 4 条）
反应条件
boron tribromide in dichloromethane T=-78 - 20°C; 20.5 h;
参考文献
MERCK PATENT GMBH; WUCHERER-PLIETKER, Margarita; WERKMANN, Daniela; GIGOUT, Anne; KUHN, Daniel; SAWATZKY, Edgar
Patent: WO2014/32755 A2, 2014 ;
Location in patent: Page/Page column 149 ;
反应条件
1: HCl 2: (i), (ii) aq. HBr, (iii) /BRN= 1098229/, HCl View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 42, # 5 p. 1723 - 1735
反应条件
(i), (ii) aq. HBr, (iii) /BRN= 1098229/, HCl; Multistep reaction;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 42, # 5 p. 1723 - 1735
反应条件
sodium hydroxide T=20°C; 1.5 h;
参考文献
MERCK PATENT GMBH; WUCHERER-PLIETKER, Margarita; WERKMANN, Daniela; GIGOUT, Anne; KUHN, Daniel; SAWATZKY, Edgar
Patent: WO2014/32755 A2, 2014 ;
Location in patent: Page/Page column 149; 150 ;
