3-苯甲酰吡啶-2-羧酸合成路线 （共 17 条）
反应条件
1: 1.) n-BuLi, N,N,N',N'-tetramethylethylenediamine / 1.) THF, a) -78 deg C, 0.5 h, b) -23 deg C, 0.5 h, 2.) a) -78 deg C, 2 h, b) 20 deg C, 3 h 2: 95 percent / 50 percent sulphuric acid / 0.75 h / Heating View Scheme
参考文献
Monatshefte fuer Chemie, , vol. 121, # 11 p. 909 - 921
反应条件
1: acetic acid anhydride / 150 °C 2: aluminium chloride View Scheme
参考文献
Chemische Berichte, , vol. 20, p. 1209
反应条件
1: SOCl2 / benzene / 0.67 h / Heating 2: triethylamine / dioxane / 24 h View Scheme
参考文献
Valter, R. E.; Batse, A. E.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, p. 199 - 200
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 1 p. 225 - 226
反应条件
beim Erhitzen auf den Schmelzpunkt;
参考文献
Bernthsen; Mettegang
Chemische Berichte, 1887 , vol. 20, p. 1209
Full Text Show Details
Jeiteles
Monatshefte fuer Chemie, 1896 , vol. 17, p. 516
反应条件
pyridine; hydroxylamine hydrochloride 0.5 h; Heating;
参考文献
Youssef, Mohamed Salah K.; Fahmy, Amin F.; Abdel Halim, Mohamed S.; Hassan, Mamdouh A.; Sauer, Juergen
Organic Preparations and Procedures International, 2005 , vol. 37, # 3 p. 247 - 256
反应条件
diphenyl-phosphinic acid; triethylamine 1.) benzene, reflux, 1 h, 2.) H2O, 1 h, heating; Yield given. Multistep reaction;
参考文献
Sollhuber-Kretzer; Troschutz
Archiv der Pharmazie, 1982 , vol. 315, # 9 p. 783 - 790
反应条件
1: 62 percent / hydrazine hydrate; acetic acid / 2 h / Heating
2: 78 percent / phosphorus oxychloride; pyridine / 1 h / 110 °C
View Scheme
参考文献
Youssef, Mohamed Salah K.; Fahmy, Amin F.; Abdel Halim, Mohamed S.; Hassan, Mamdouh A.; Sauer, Juergen
Organic Preparations and Procedures International, 2005 , vol. 37, # 3 p. 247 - 256
