1-氯-4-(3-氯丙烷基)苯合成路线 （共 5 条）
反应条件
bis(trichloromethyl) carbonate; triethylamine in dichloromethane Schlenk techniqueInert atmosphere;
参考文献
Gao, Ke; Yoshikai, Naohiko
Journal of the American Chemical Society, 2013 , vol. 135, # 25 p. 9279 - 9282
反应条件
1: triethylamine / CH2Cl2 / Ambient temperature
2: 78 percent / CH2Cl2 / Ambient temperature
3: 74 percent / KOH / aq. ethanol / 5 h / Heating
View Scheme
参考文献
Albright; DeVries; Largis; Miner; Reich; Schaffer; Shepherd; Upeslacis
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1378 - 1393
反应条件
hydrogenchloride in ethanol
参考文献
Boehringer Ingelheim Ltd.
Patent: US4725597 A1, 1988 ;
反应条件
triethylamine in dichloromethane
Ambient temperature;
参考文献
Albright; DeVries; Largis; Miner; Reich; Schaffer; Shepherd; Upeslacis
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1378 - 1393
反应条件
1: triethylamine / CH2Cl2 / Ambient temperature
2: 97 percent / KOH / aq. ethanol / 5 h / Heating
View Scheme
参考文献
Albright; DeVries; Largis; Miner; Reich; Schaffer; Shepherd; Upeslacis
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1378 - 1393
