反应条件
1: 1.) n-butyllithium / 1.) THF, hexane, -78 deg C, 20 min, 2.) room temperature, 2 h 2: 1.) sodium hexamethyldisilylamide / 1.) THF, -78 deg C, 30 min, 2.) -78 deg C, 1 h 3: 94 percent / n-butyllithium / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Heitsch; Henning; Kleemann; Linz; Nickel; Ruppert; Urbach; Wagner
Journal of Medicinal Chemistry, 1993 , vol. 36, # 19 p. 2788 - 2800
